• The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma 

      Rasheed, Kashif; Moens, Ugo; policastro, benedetta; Johnsen, John Inge; Koljonen, Virve; Sihto, Harri; Lui, Weng-Onn; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-28)
      Merkel cell polyomavirus (MCPyV) is a causal factor in Merkel cell carcinoma (MCC). The oncogenic potential is mediated through its viral oncoproteins large T-antigen (LT) and small T-antigen (sT). Cytokines produced by tumor cells play an important role in cancer pathogenesis, and viruses affect their expression. Therefore, we compared human cytokine and receptor transcript levels in virus ...